Two sample MR report
RPS26_Conventional Dendritic Cell against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 6 | -0.0490267 | 0.0606124 | 0.4639611 |
| Weighted median | 6 | -0.0484099 | 0.0106607 | 0.0000056 |
| Inverse variance weighted | 6 | -0.0479369 | 0.0086809 | 0.0000000 |
| Simple mode | 6 | -0.0528788 | 0.0142028 | 0.0136679 |
| Weighted mode | 6 | -0.0494696 | 0.0139892 | 0.0166284 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 1.304388 | 4 | 0.8606306 |
| Inverse variance weighted | 1.304718 | 5 | 0.9344455 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0006218 | 0.0342274 | 0.9863751 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0005055 | 0 | TRUE | 0.0335686 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
